Drug Delivery
Development of innovative conjugation concepts is a key aspect of our efforts in drug delivery. Our conjugation techniques have long been recognised as useful tools for modifying in vivo drug properties with respect to biotransport properties, clearance rates, and so on.
Services
- Prodrugs : Design and synthesize sophisticated prodrugs to address issues such as improvement of therapeutic index, chemical stability, altered pharmacokinetics, altered drug transport and improved bio-availability through increased water solubility.
- Molecules : Expertise in drugs related to natural products, e.g., alkaloids, heterocycles, nucleosides, carbohydrates and peptides.
- Biodegradable bonds: Making of biodegradable bonds using amide, oxime, thiazolidine, hydrazone, thioester, schiff’s base, maleimide, disulfide etc., and includes a variety of mono and heterobifunctional linkers.
- Cell targeting : Targeting of drugs can be achieved in a number of ways usually conjugating the drug of interest with specific ligands or by engineering the properties of the carrier system. Our conjugations are effective and vital, with target cell specific ligands increases selectivity and efficacy.
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